This invitation only breakfast is for those currently serving as a committee member on one of the following ASHI Committees: ARB, ACHI, Awards, Audit, Bylaws, Directors’ Affairs, Education, External Affairs, Finance, International Affairs, Info Technology, Leadership Development, Marketing, Membership, NCAC, Program Planning, Publications, PT Committee, QAS, STIC, or Technologists’ Affairs Committee.
ASHI sponsors several awards to recognize scientific accomplishments and contributions to the fields of histocompatibility and immunogenetics, and service to the society. Join us in awarding the 2024 recipients for the Distinguished Scientist, Outstanding Technologist and the J. Marilyn MacQueen Rising Star.
Understanding ABO-histocompatibility will allow improved risk assessment for ABO-incompatible organ transplantation. This presentation will cover emerging glycomics tools to improve accuracy of risk assessment. The ABO glycan microarray and ABO single antigen bead luminex assay for detection and precise characterization of ABO subtype specific antibodies will be especially helpful. Additionally, ABO subtype-specific monoclonal antibodies and ABO genotyping will allow full donor and recipient profile and tissue-specific antigen expression. These tools can accompany crucial information generated by HLA risk assessment.
Leaders in the field of thoracic transplantation will speak on cutting-edge procedures, discuss new and existing biomarkers, and describe current approaches to optimize outcomes for heart and lung transplant candidates. Furthermore, advances in the operating room procedures as well as post-transplant tools to monitor allograft health will be discussed. Additionally, new studies in lung transplantation that focus on approaches to overcome histocompatibility barriers and increase donor options for HLA sensitized candidates will be presented
With multiple approaches to assess HLA eplets and molecular mismatches, there is intense interest in improving the sensitivity and biological relevance of these models by identifying those most likely to stimulate an alloimmune response. This is widely being called “immunogenicity,” but the definitions and biology of antigenic vs. immunogenic properties need to be considered as we move forward. This session will cover features of antigens that make them more or less able to be recognized by T/B cells, then discuss the role of antigen presenting cells and their activation state as determinants of adaptive immune activation. Lastly, we will translate these premises to the biology of B cells and alloantibody production.
This workshop will include a “LIVE HLA antibody analysis challenge” to compare new and developing analytical tools with the goal of improving analytical validity within HLA antibody testing and DSA assignments. Speakers will be challenged with the same single antigen bead csv files and discuss their results “live” during the workshop. We will engage the speakers and audience in active discussion on improved accuracy and the practicality of implementation into clinical workflows.
This workshop is designed to review policy and practice related to ABO-incompatible transplantation. ABO-histocompatibility and the current methods used to determine ABO immune risk assessment will be reviewed. The session will finish with a panel discussion related to current practice and potential future directions of ABO-incompatible practice in renal and pediatric heart transplantation.
This invitation only reception is for Director in Training attendees to network with other DITs and members of the ASHI Board. Enjoy light fare and beverages.
This invitation only reception is for International attendees of the ASHI Annual Meeting to mingle and learn more about the meeting and the society.
This invitation only reception is ASHI's thank you to all of our hard-working inspectors. Enjoy time with your colleagues and light fare and beverages.