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Plenary

Featured Topic: Immunogenetics & Disease

Monday, October 21, 2024
12:30 PM – 5:00 PM US PDT
Location: Marquis Northeast

This session will provide broad perspectives on the history, contemporary era, and future of immunogenetics. It will open with historical perspectives on the immunogenetics of disease, followed by modern immunogenetic perspectives on Type-1-Diabetes, infectious disease, and adverse drug reactions. The second half of the session will showcase new approaches for understanding the evolution and organization of the HLA region, the impact of archaic gene variants on the immunity of modern humans, and novel insights into KIR-HLA and CD8-NK cell interactions.

Session developed by Steve Mack, program planning committee.

To learn more please click here.

Presentations:

  • 12:30 PM – 1:00 PM US PDT
    Immunogenetics and Disease: A Brief History

    Speaker: Henry Erlich, PhD – UCSF

  • 1:00 PM – 1:30 PM US PDT
    Fifty years of HLA and T1D risk: looking back, and looking forward

    Speaker: Janelle Noble, PhD – UCSF

  • 1:30 PM – 2:00 PM US PDT
    The Immunogenetics of COVID-19

    Speaker: Jill Hollenbach, PhD, MPH – University of California San Francisco

  • 2:00 PM – 2:30 PM US PDT
    Immunogenetics of Severe T-cell Mediated Adverse Drug Reactions: Insights into pathogenesis, prevention and diagnosis

    Speaker: Elizabeth Phillips, MD – Vanderbilt University Medical Center

  • 2:40 PM – 3:10 PM US PDT
    Genetic Variation and Evolutionary Dynamics of MHC Class II and III Genes: Insights from 130 Phased Genome Assemblies

    Speaker: Mark Christian Loftus, PhD – Clemson University

  • 3:10 PM – 3:40 PM US PDT
    TCR Recognition of Lipids and Metabolites

    Speaker: Jamie Rossjohn, PhD, FRS – Monash University

  • 3:40 PM – 4:10 PM US PDT
    Archaic KIR3DL1 enhances HLA binding to inhibit NK cells throughout Oceania

    Speaker: Paul Norman, PhD – University of Colorado School of Medicine

  • 4:10 PM – 4:40 PM US PDT
    NKp44/HLA-DP-dependent regulation of CD8 effector T cells by NK cells

    Speaker: Benedetta Padoan, MSc – Leibniz Institute of Virology

  • 4:40 PM – 5:00 PM US PDT
    Speaker Panel